@Bedo13 please update
you must be doing it wrong, then. make sure only 2 mods are turned on and save preferences is on. if you decide to use all three, make sure you turn one off before exiting the game. this always worked for me, no reinstallation needed.
I am doing that now on unsigned and it doesn't work. Signed doesn't work either. I do exactly that.
Launch the game, allow display over other apps, open mod menu, enable bottom two, save preferences, minimize, accept in-game. Exit with only two and upon relaunch neither works.
Also, how do you deal with the frozen Talents screen upon rolling one? My talents have been consistently frozen on first roll ever since it first happened, throughout all the reinstalls.